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Publications

  • Brown, J. R., Fuster, M.M., Whisenant, T., and Esko, J. D. Expression patterns of α2,3-sialyltransferases and α1,3-Fucosylatransferases determine the mode of sialyl Lewis X inhibition by disaccharide decoys. (2003) J Biol Chem 278(26), 23352-23359.

  • Editorial – Glycobiology: Turning Sweet on Cancer. Science 301 11 July 2003. Editorial featuring ZP103, that highlights new therapies that target glycans.

  • Brown, J.R., Fuster, M.M. Li, R. Varki, N., Glass, C.A. and Esko, J.D. 2006. A disaccharide-based inhibitor of glycosylation attenuates metastatic tumor cell dissemination. Clin Cancer Res 12, Accepted for publication.

  • Brown JR, Crawford BE, and Esko, JD (2007) Glycan antagonists and inhibitors: a fount for drug discovery. Crit Rev Biochem Mol Biol. 2007 42(6):481-515. Review.

  • Brown JR, et al., Small Molecule Inhibitors of Glycosaminoglycan Biosynthesis as Substrate Optimization Therapy for Mucopolysaccharidosis. International Congress of Inborn Errors of Metabolism 2009; Poster 366. Click HERE to download a copy of the poster.

  • Brown JR, et.al., Glycan-Based BioMarkers for the Mucopolysaccharidoses: The Sensi-Pro™ Substrate Assay. International Congress of Inborn Errors of Metabolism 2009; Poster 365. Click HERE to download a copy of the poster.

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